Invention Grant
US08298797B2 Δ-9 elongases and their use in making polyunsaturated fatty acids 有权
&Dgr; -9延伸酶及其在制备多不饱和脂肪酸中的应用

Δ-9 elongases and their use in making polyunsaturated fatty acids
Abstract:
The present invention relates to Δ9 elongases, which have the ability to convert linoleic acid (LA; 18:2 ω-6) to eicosadienoic acid (EDA; 20:2 ω-6) and/or α-linolenic acid (ALA; 18:3 ω-3) to eicosatrienoic acid (ETrA; 20:3 ω-3). Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding Δ9 elongases along with a method of making long-chain polyunsaturated fatty acids (PUFAs) using these Δ9 elongases in oleaginous yeast are disclosed.
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