发明授权
- 专利标题： Quinolinone derivatives as PARP and TANK inhibitors
- 专利标题（中）： 喹啉酮衍生物作为PARP和TANK抑制剂
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申请号： US12529142申请日： 2008-03-07
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公开(公告)号： US08299256B2公开(公告)日： 2012-10-30
- 发明人: Jorge Eduardo Vialard , Patrick René Angibaud , Laurence Anne Mevellec , Christophe Meyer , Eddy Jean Edgard Freyne , Isabelle Noëlle Constance Pilatte , Bruno Roux , Elisabeth Thérèse Jeanne Pasquier , Xavier Marc Bourdrez , Christophe Denis Adelinet , Laurence Françoise Bernadette Marconnet-Decrane , Jacqueline Anne Macritchie , James Edward Stewart Duffy , Andrew Pate Owens , Pierre-Henri Storck , Virginie Sophie Poncelet
- 申请人： Jorge Eduardo Vialard , Patrick René Angibaud , Laurence Anne Mevellec , Christophe Meyer , Eddy Jean Edgard Freyne , Isabelle Noëlle Constance Pilatte , Bruno Roux , Elisabeth Thérèse Jeanne Pasquier , Xavier Marc Bourdrez , Christophe Denis Adelinet , Laurence Françoise Bernadette Marconnet-Decrane , Jacqueline Anne Macritchie , James Edward Stewart Duffy , Andrew Pate Owens , Pierre-Henri Storck , Virginie Sophie Poncelet
- 申请人地址： BE Beerse
- 专利权人： Janssen Pharmaceutica NV
- 当前专利权人： Janssen Pharmaceutica NV
- 当前专利权人地址： BE Beerse
- 优先权： EP07103788 20070308
- 国际申请： PCT/EP2008/052764 WO 20080307
- 国际公布： WO2008/107478 WO 20080912
- 主分类号： C07D215/38
- IPC分类号： C07D215/38
摘要：
The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, n, m and X have defined meanings.
公开/授权文献
- US20100168065A1 QUINOLINONE DERIVATIVES AS PARP AND TANK INHIBITORS 公开/授权日：2010-07-01
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