发明授权
- 专利标题: Pool and superpool matrix coding and decoding designs and methods
- 专利标题(中): 池和超级矩阵编码和解码设计和方法
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申请号: US10841375申请日: 2004-05-05
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公开(公告)号: US08301388B2公开(公告)日: 2012-10-30
- 发明人: Keith E. Stormo , QuanZhou Tao , Robert Bogden
- 申请人: Keith E. Stormo , QuanZhou Tao , Robert Bogden
- 申请人地址: US WA Pullman
- 专利权人: Amplicon Express, Inc.
- 当前专利权人: Amplicon Express, Inc.
- 当前专利权人地址: US WA Pullman
- 主分类号: G01N33/50
- IPC分类号: G01N33/50
摘要:
This application pertains to construction of pooled biological material such as DNA, RNA, proteins and the like that are able to be screened by a wide variety of methods such as PCR (Polymerase Chain Reaction), DNA/DNA hybridization, DNA/RNA hybridization, RNA/RNA hybridization, single strand DNA probing, protein/protein hybridization and a wide variety of additional methods. Our new method for construction of pools and superpools for screening differs in that the complete set is systematically divided into a variety of smaller subsets which are then re-pooled to make the final screening pools. This pooled material can be from individual samples or a population of samples. In order to reduce the analysis time, materials and expense, the pooling of high resolution small pools in a matrix allows for a lower number of user experiments to have higher resolution (as if the researcher had analyzed the complete set of small pools).