Invention Grant
US08304448B2 Method for the treatment of metabolic disorder containing benzazole derivatives as an active ingredient
有权
用于治疗含有苯并唑衍生物作为活性成分的代谢紊乱的方法
- Patent Title: Method for the treatment of metabolic disorder containing benzazole derivatives as an active ingredient
- Patent Title (中): 用于治疗含有苯并唑衍生物作为活性成分的代谢紊乱的方法
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Application No.: US12442895Application Date: 2007-09-27
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Publication No.: US08304448B2Publication Date: 2012-11-06
- Inventor: Hyun Sun Lee , Kyeong Lee , Jung Joon Lee , Young Kook Kim , Mun-Chual Rho , Jeong Hyung Lee , Young Soo Hong , Hye-Ran Park , Chul-Ho Lee , Yongseok Choi
- Applicant: Hyun Sun Lee , Kyeong Lee , Jung Joon Lee , Young Kook Kim , Mun-Chual Rho , Jeong Hyung Lee , Young Soo Hong , Hye-Ran Park , Chul-Ho Lee , Yongseok Choi
- Applicant Address: KR Daejeon-Si
- Assignee: Korea Research Institute of Bioscience and Biotechnology
- Current Assignee: Korea Research Institute of Bioscience and Biotechnology
- Current Assignee Address: KR Daejeon-Si
- Agency: Greenlee Sullivan P.C.
- Priority: KR10-2006-0094131 20060927
- International Application: PCT/KR2007/004724 WO 20070927
- International Announcement: WO2008/039008 WO 20080403
- Main IPC: A61K31/40
- IPC: A61K31/40 ; A61K31/405
Abstract:
Disclosed is a composition for the prevention and treatment of metabolic diseases, which comprises a benzazole derivative as an active ingredient. The benzazole derivative has inhibitory activity against DGAT (diacylglycerol acyltransferase), which causes metabolic diseases such as obesity and diabetes in the process of lipid metabolism. With the ability to effectively control lipid metabolism and energy metabolism, thus, the composition is useful in the prevention and treatment of metabolic diseases, such as obesity and diabetes.
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