发明授权
US08329709B2 5H-cyclopenta[D]pyrimidines as AKT protein kinase inhibitors
有权
5H-环戊二烯并[D]嘧啶作为AKT蛋白激酶抑制剂
![5H-cyclopenta[D]pyrimidines as AKT protein kinase inhibitors](/docs/US/2012-12-11/US08329709B2/abs.jpg.600x600.jpg)
- 专利标题： 5H-cyclopenta[D]pyrimidines as AKT protein kinase inhibitors
- 专利标题（中）： 5H-环戊二烯并[D]嘧啶作为AKT蛋白激酶抑制剂
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申请号： US12812377申请日： 2009-01-09
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公开(公告)号： US08329709B2公开(公告)日： 2012-12-11
- 发明人: Anna L. Banka , Josef R. Bencsik , James Blake , Martin Hentemann , Nicholas C. Kallan , Jun Liang , Ian S. Mitchell , Stephen T. Schlachter , Eli M. Wallace , Rui Xu , Tony P. Tang
- 申请人： Anna L. Banka , Josef R. Bencsik , James Blake , Martin Hentemann , Nicholas C. Kallan , Jun Liang , Ian S. Mitchell , Stephen T. Schlachter , Eli M. Wallace , Rui Xu , Tony P. Tang
- 申请人地址： US CA South San Francisco US CO Boulder
- 专利权人： Genentech, Inc.,Array BioPharma Inc.
- 当前专利权人： Genentech, Inc.,Array BioPharma Inc.
- 当前专利权人地址： US CA South San Francisco US CO Boulder
- 代理机构： Viksnins Harris & Padys PLLP
- 国际申请： PCT/US2009/030617 WO 20090109
- 国际公布： WO2009/089462 WO 20090716
- 主分类号： A61K31/517
- IPC分类号： A61K31/517 ; C07D239/70
![5H-cyclopenta[D]pyrimidines as AKT protein kinase inhibitors](/abs-image/US/2012/12/11/US08329709B2/abs.jpg.150x150.jpg)
摘要：
Compounds of Formula I are useful for inhibiting AKT protein kinases. Methods using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed. Formula (I).
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