发明授权
- 专利标题： Macrocyclic compounds useful as pharmaceuticals
- 专利标题（中）： 用作药物的大环化合物
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申请号： US12839873申请日： 2010-07-20
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公开(公告)号： US08329742B2公开(公告)日： 2012-12-11
- 发明人: Roch Boivin , Kenichi Chiba , Jesse Chow , Hong Du , Yoshihito Eguchi , Masanori Fujita , Masaki Goto , Fabian Gusovsky , Jean-Christophe Harmange , Atsushi Inoue , Yimin Jiang , Megumi Kawada , Takatoshi Kawai , Yoshiyuki Kawakami , Akifumi Kimura , Makoto Kotake , Yoshikazu Kuboi , Charles-André Lemelin , Xiang-Yi Li , Tomohiro Matsushima , Yoshiharu Mizui , Kenzo Muramoto , Hideki Sakurai , Yong-Chun Shen , Hiroshi Shirota , Mark Spyvee , Isao Tanaka , John (Yuan) Wang , Satoshi Yamamoto , Naoki Yoneda
- 申请人： Roch Boivin , Kenichi Chiba , Jesse Chow , Hong Du , Yoshihito Eguchi , Masanori Fujita , Masaki Goto , Fabian Gusovsky , Jean-Christophe Harmange , Atsushi Inoue , Yimin Jiang , Megumi Kawada , Takatoshi Kawai , Yoshiyuki Kawakami , Akifumi Kimura , Makoto Kotake , Yoshikazu Kuboi , Charles-André Lemelin , Xiang-Yi Li , Tomohiro Matsushima , Yoshiharu Mizui , Kenzo Muramoto , Hideki Sakurai , Yong-Chun Shen , Hiroshi Shirota , Mark Spyvee , Isao Tanaka , John (Yuan) Wang , Satoshi Yamamoto , Naoki Yoneda
- 申请人地址： JP Tokyo
- 专利权人： EISAI Co., Ltd.
- 当前专利权人： EISAI Co., Ltd.
- 当前专利权人地址： JP Tokyo
- 代理机构： Lathrop & Gage LLP
- 代理商 Brian C. Trinque
- 主分类号： A61K31/355
- IPC分类号： A61K31/355 ; C07D313/00
摘要：
The present invention provides methods for the use of compounds having formula (I) in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis, wherein R1-R11, t, X, Y, Z, and n are as defined herein.
公开/授权文献
- US20110144101A1 MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS 公开/授权日：2011-06-16