A tire-wheel assembly and disassembly method is disclosed wherein relative shifting of a tire and a wheel when braking and/or cornering can be suppressed without negatively affecting tire replacement workability. Specifically, a tire-wheel assembly has a wheel constructed from an electrically conductive material and a tire assembled on an outer peripheral side of the wheel, wherein an electrically conductive layer is formed on at least a part of a wheel contact surface of the tire, and an electrically debonding adhesive comprising an ionic liquid is interposed between the electrically conductive layer of the tire and the wheel. When disassembling this tire-wheel assembly, the tire is removed from the wheel after voltage is applied between the wheel and the electrically conductive layer of the tire and electricity is passed through the electrically debonding adhesive.