发明授权
- 专利标题： Inhibitors of P38
- 专利标题（中）： P38抑制剂
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申请号： US13107802申请日： 2011-05-13
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公开(公告)号： US08338412B2公开(公告)日： 2012-12-25
- 发明人: Guy W. Bemis , Francesco G. Salituro , John P. Duffy , John E. Cochran , Edmund M. Harrington , Mark A. Murcko , Keith P. Wilson , Michael Su , Vincent P. Galullo
- 申请人： Guy W. Bemis , Francesco G. Salituro , John P. Duffy , John E. Cochran , Edmund M. Harrington , Mark A. Murcko , Keith P. Wilson , Michael Su , Vincent P. Galullo
- 申请人地址： US MA Cambridge
- 专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人地址： US MA Cambridge
- 代理机构： VLP Law Group LLP
- 代理商 David A. Roise
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/5025
摘要：
The present invention relates to inhibitors of p38, a mammalian protein kinase involved cell proliferation, cell death and response to extracellular stimuli. The invention also relates to methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing those compositions in the treatment and prevention of various disorders.
公开/授权文献
- US20110281878A1 INHIBITORS OF p38 公开/授权日：2011-11-17
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