发明授权
US08338476B2 Compositions and methods of sensitizing methicillin resistant Staphylococcus aureus to beta-lactam antibiotics
有权
使耐甲氧西林金黄色葡萄球菌对β-内酰胺抗生素敏感的组合物和方法
- 专利标题： Compositions and methods of sensitizing methicillin resistant Staphylococcus aureus to beta-lactam antibiotics
- 专利标题（中）： 使耐甲氧西林金黄色葡萄球菌对β-内酰胺抗生素敏感的组合物和方法
-
申请号： US12095960申请日： 2005-12-29
-
公开(公告)号： US08338476B2公开(公告)日： 2012-12-25
- 发明人: Paul Stapleton , Yukihiko Hara , Peter Taylor
- 申请人： Paul Stapleton , Yukihiko Hara , Peter Taylor
- 申请人地址： JP Tokyo GB London
- 专利权人： Mitsui Norin Co, Ltd.,The School of Pharmacy, University of London
- 当前专利权人： Mitsui Norin Co, Ltd.,The School of Pharmacy, University of London
- 当前专利权人地址： JP Tokyo GB London
- 代理机构： Fish & Associates, PC
- 国际申请： PCT/US2005/047570 WO 20051229
- 国际公布： WO2007/075176 WO 20070705
- 主分类号： A61K31/352
- IPC分类号： A61K31/352 ; A61K31/397 ; A01N43/16 ; A01N43/44 ; A01N43/90
摘要：
Contemplated methods and compositions further increase susceptibility of sensitized MRSA against various antibiotic drugs. Most preferably, the MRSA is already sensitized with a galloylated catechin (e.g., ECG), and further sensitization is achieved by exposure to a non-galloylated catechin (e.g., EC), and most preferably the corresponding non-galloylated catechin.
公开/授权文献
信息查询
