发明授权
- 专利标题: Treatment or prevention of cancer and precancerous disorders
- 专利标题(中): 治疗或预防癌症和癌前期疾病
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申请号: US12557022申请日: 2009-09-10
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公开(公告)号: US08357720B2公开(公告)日: 2013-01-22
- 发明人: Herbert Weissbach , Lionel Resnick , David Binninger
- 申请人: Herbert Weissbach , Lionel Resnick , David Binninger
- 申请人地址: US FL Boca Raton
- 专利权人: Florida Atlantic University
- 当前专利权人: Florida Atlantic University
- 当前专利权人地址: US FL Boca Raton
- 代理机构: Novak Druce Quigg LLP
- 主分类号: A61K31/255
- IPC分类号: A61K31/255 ; A61K33/40
摘要:
The NSAID, sulindac and/or its metabolites and derivatives, in combination with an agent that generates or induces reactive oxygen species (ROS), significantly enhances the killing of abnormal cells but does not affect normal cells. This effect occurs at concentrations of each compound that individually have little or no activity directed against the abnormal cells.
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