Invention Grant
- Patent Title: Macrocyclic compound
- Patent Title (中): 大环化合物
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Application No.: US12529222Application Date: 2008-02-29
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Publication No.: US08362236B2Publication Date: 2013-01-29
- Inventor: Nobuo Shimma , Takuo Tsukuda , Hiroshi Koyano , Atsushi Suda , Tadakatsu Hayase , Kihito Hada , Ken-Ichi Kawasaki , Susumu Komiyama , Naomi Ono , Toshikazu Yamazaki , Ryoichi Saitoh , Masami Kohchi , Kiyoshi Hasegawa
- Applicant: Nobuo Shimma , Takuo Tsukuda , Hiroshi Koyano , Atsushi Suda , Tadakatsu Hayase , Kihito Hada , Ken-Ichi Kawasaki , Susumu Komiyama , Naomi Ono , Toshikazu Yamazaki , Ryoichi Saitoh , Masami Kohchi , Kiyoshi Hasegawa
- Applicant Address: JP Tokyo
- Assignee: Chugai Seiyaku Kabushiki Kaisha
- Current Assignee: Chugai Seiyaku Kabushiki Kaisha
- Current Assignee Address: JP Tokyo
- Agency: Fish & Richardson P.C.
- Priority: JP2007-052072 20070301
- International Application: PCT/JP2008/053599 WO 20080229
- International Announcement: WO2008/105526 WO 20080904
- Main IPC: C07D497/08
- IPC: C07D497/08 ; C07D513/08 ; C07D513/20 ; A61K31/529 ; A61K31/53 ; A61K31/5377 ; A61P35/00
Abstract:
The present invention provides a novel class of compounds that have the activity of inhibiting HSP90 enzyme and are useful as anti-cancer agents or such, and compounds that are useful as synthetic intermediates thereof. Specifically, the present invention provides compounds represented by the following formula (1), and pharmaceutically acceptable salts thereof: wherein X, R1, R2, R3, R4, R5, R6, R7, L1, L2, and L3 are as defined in the specification.
Public/Granted literature
- US20100056510A1 Macrocyclic Compound Public/Granted day:2010-03-04
Information query
