- 专利标题: Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles
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申请号: US13596971申请日: 2012-08-28
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公开(公告)号: US08372424B2公开(公告)日: 2013-02-12
- 发明人: Stephen A. Berry , Pamela J. Fereira , Houdin Dehnad , Anna Muchnik
- 申请人: Stephen A. Berry , Pamela J. Fereira , Houdin Dehnad , Anna Muchnik
- 申请人地址: US CA Hayward
- 专利权人: Intarcia Therapeutics, Inc.
- 当前专利权人: Intarcia Therapeutics, Inc.
- 当前专利权人地址: US CA Hayward
- 代理商 Gary R. Fabian; Barbara G. McClung
- 主分类号: A61F2/00
- IPC分类号: A61F2/00 ; A61K9/14 ; A61K47/30 ; A61K47/00
摘要:
This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperatures ranging from cold to body temperature for long periods of time. The formulations are capable of being uniformly delivered from drug delivery systems at an exit shear rate of between about 1 to 1×10−7 reciprocal second.
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