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1.发明授权Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles 有权稳定的非水性单相粘性载体和使用这种载体的制剂公开(公告)号：US08992961B2
公开(公告)日：2015-03-31
申请号：US13219262
申请日：2011-08-26
IPC分类号： A61F13/00 , A61K47/00 , A61F2/00 , A61K49/00 , C12M1/34 , C12M1/36 , A61K9/00 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/32 , A61K47/44
CPC分类号： A61K38/27 , A61K9/0004 , A61K9/0024 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/26 , A61K47/32 , A61K47/44 , Y10S514/937 , Y10T29/49826
摘要： This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperatures ranging from cold to body temperature for long periods of time. The formulations are capable of being uniformly delivered from drug delivery systems at an exit shear rate of between about 1 to 1×10−7 reciprocal second.
摘要翻译： 本发明涉及稳定的非水性单相粘性载体和利用这种载体的制剂。 制剂包含均匀悬浮在载体中的至少一种有益剂。 该制剂能够在从寒冷到体温的温度下长时间储存。 制剂能够以约1至1×10-7倒数第二次的出口剪切速率从药物递送系统均匀递送。
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2.发明申请STABLE NON-AQUEOUS SINGLE PHASE VISCOUS VEHICLES AND FORMULATIONS UTILIZING SUCH VEHICLES 有权稳定的非水性单相VISCOUS车辆和使用这种车辆的配方公开(公告)号：US20120208754A1
公开(公告)日：2012-08-16
申请号：US13454063
申请日：2012-04-23
摘要： This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperatures ranging from cold to body temperature for long periods of time. The formulations are capable of being uniformly delivered from drug delivery systems at an exit shear rate of between about 1 to 1×10−7 reciprocal second.
摘要翻译： 本发明涉及稳定的非水性单相粘性载体和利用这种载体的制剂。 制剂包含均匀悬浮在载体中的至少一种有益剂。 该制剂能够在从寒冷到体温的温度下长时间储存。 制剂能够以约1至1×10-7倒数第二次的出口剪切速率从药物递送系统均匀递送。
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3.发明申请STABLE NON-AQUEOUS SINGLE PHASE VISCOUS VEHICLES AND FORMULATIONS UTILIZING SUCH VEHICLES 有权稳定的非水性单相VISCOUS车辆和使用这种车辆的配方公开(公告)号：US20110308061A1
公开(公告)日：2011-12-22
申请号：US13219262
申请日：2011-08-26
IPC分类号： B23P11/00
CPC分类号： A61K38/27 , A61K9/0004 , A61K9/0024 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/26 , A61K47/32 , A61K47/44 , Y10S514/937 , Y10T29/49826
摘要： This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperatures ranging from cold to body temperature for long periods of time. The formulations are capable of being uniformly delivered from drug delivery systems at an exit shear rate of between about 1 to 1×10−7 reciprocal second.
摘要翻译： 本发明涉及稳定的非水性单相粘性载体和利用这种载体的制剂。 制剂包含均匀悬浮在载体中的至少一种有益剂。 该制剂能够在从寒冷到体温的温度下长时间储存。 制剂能够以约1至1×10-7倒数第二次的出口剪切速率从药物递送系统均匀递送。
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4.发明申请Stable non- aqueous single phase viscous vehicles and formulations utlizing such vehicles 有权稳定的非水性单相粘性载体和使用这种载体的配方公开(公告)号：US20080226625A1
公开(公告)日：2008-09-18
申请号：US12077117
申请日：2008-03-17
IPC分类号： A61K39/395 , A61K47/00 , A61K38/02 , A61K38/16 , A61K31/7052 , A61K35/76
CPC分类号： A61K38/27 , A61K9/0004 , A61K9/0024 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/26 , A61K47/32 , A61K47/44 , Y10S514/937 , Y10T29/49826
摘要： This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperatures ranging from cold to body temperature for long periods of time. The formulations are capable of being uniformly delivered from drug delivery systems at an exit shear rate of between about 1 to 1×10−7 reciprocal second.
摘要翻译： 本发明涉及稳定的非水性单相粘性载体和利用这种载体的制剂。 制剂包含均匀悬浮在载体中的至少一种有益剂。 该制剂能够在从寒冷到体温的温度下长时间储存。 制剂能够以约1至1×10 -7 -7倒数第二次的出口剪切速率从药物递送系统均匀递送。
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5.发明授权Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle 有权稳定的非水性单相粘性载体和使用这种载体的制剂公开(公告)号：US07258869B1
公开(公告)日：2007-08-21
申请号：US09497422
申请日：2000-02-03
CPC分类号： A61K38/27 , A61K9/0004 , A61K9/0024 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/26 , A61K47/32 , A61K47/44 , Y10S514/937 , Y10T29/49826
摘要： This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperatures ranging from cold to body temperature for long periods of time. The formulations are capable of being uniformly delivered from drug delivery systems at an exit shear rate of between about 1 to 1×10−7 reciprocal second.
摘要翻译： 本发明涉及稳定的非水性单相粘性载体和利用这种载体的制剂。 制剂包含均匀悬浮在载体中的至少一种有益剂。 该制剂能够在从寒冷到体温的温度下长时间储存。 制剂能够以约1至1×10 -7 -7倒数第二次的出口剪切速率从药物递送系统均匀递送。
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公开(公告)号：US20070078096A1
公开(公告)日：2007-04-05
申请号：US11356339
申请日：2006-02-16
申请人： Michel Cormier , Sara Sendelbeck , Anna Muchnik , Iris Leung
发明人： Michel Cormier , Sara Sendelbeck , Anna Muchnik , Iris Leung
CPC分类号： A61K38/27 , A61K9/0009 , A61K9/0014 , A61K38/28 , A61K47/183 , A61K47/38 , A61N1/0424 , A61N1/044 , A61N1/0444 , A61N1/30 , A61N1/327
摘要： Buffered drug formulations for transdermal electrotransport delivery are disclosed. The formulations utilize a dipeptide as a buffer and allow for more efficient electrotransport delivery of drugs, e.g., polypeptide drugs, via the transdermal route.
摘要翻译： 公开了用于透皮电转运递的缓冲药物制剂。 制剂利用二肽作为缓冲液，并允许通过经皮途径更有效地电转运药物，例如多肽药物。
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7.发明授权Stable non-aqueous single phase viscous vehicles and formulations utlizing such vehicles 有权稳定的非水单相粘性车辆和使用这种车辆的配方公开(公告)号：US08173150B2
公开(公告)日：2012-05-08
申请号：US13043288
申请日：2011-03-08
摘要： This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperatures ranging from cold to body temperature for long periods of time. The formulations are capable of being uniformly delivered from drug delivery systems at an exit shear rate of between about 1 to 1×10−7 reciprocal second.
摘要翻译： 本发明涉及稳定的非水性单相粘性载体和利用这种载体的制剂。 制剂包含均匀悬浮在载体中的至少一种有益剂。 该制剂能够在从寒冷到体温的温度下长时间储存。 制剂能够以约1至1×10-7倒数第二次的出口剪切速率从药物递送系统均匀递送。
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8.发明授权Stable non- aqueous single phase viscous vehicles and formulations utilizing such vehicles 有权稳定的非水性单相粘性载体和利用这种载体的制剂公开(公告)号：US08048438B2
公开(公告)日：2011-11-01
申请号：US12077117
申请日：2008-03-17
IPC分类号： A61F13/00
CPC分类号： A61K38/27 , A61K9/0004 , A61K9/0024 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/26 , A61K47/32 , A61K47/44 , Y10S514/937 , Y10T29/49826
摘要： This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperatures ranging from cold to body temperature for long periods of time. The formulations are capable of being uniformly delivered from drug delivery systems at an exit shear rate of between about 1 to 1×10−7 reciprocal second.
摘要翻译： 本发明涉及稳定的非水性单相粘性载体和利用这种载体的制剂。 制剂包含均匀悬浮在载体中的至少一种有益剂。 该制剂能够在从寒冷到体温的温度下长时间储存。 制剂能够以约1至1×10-7倒数第二次的出口剪切速率从药物递送系统均匀递送。
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公开(公告)号：US20050171021A1
公开(公告)日：2005-08-04
申请号：US10164095
申请日：2002-06-04
申请人： Michel Cormier , Sara Sendelbeck , Anna Muchnik , Iris Leung
发明人： Michel Cormier , Sara Sendelbeck , Anna Muchnik , Iris Leung
CPC分类号： A61K47/183 , A61K9/0009
摘要： Buffered drug formulations for transdermal electrotransport delivery are disclosed. The formulations utilize a dipeptide as a buffer and allow for more efficient electrotransport delivery of drugs, e.g., polypeptide drugs, via the transdermal route.
摘要翻译： 公开了用于透皮电转运递的缓冲药物制剂。 制剂利用二肽作为缓冲液，并允许通过经皮途径更有效地电转运药物，例如多肽药物。
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10.发明授权Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles 有权稳定的非水性单相粘性载体和使用这种载体的制剂公开(公告)号：US08268341B2
公开(公告)日：2012-09-18
申请号：US13454063
申请日：2012-04-23
摘要： This invention relates to stable non-aqueous single phase viscous vehicles and to formulations utilizing such vehicles. The formulations comprise at least one beneficial agent uniformly suspended in the vehicle. The formulation is capable of being stored at temperatures ranging from cold to body temperature for long periods of time. The formulations are capable of being uniformly delivered from drug delivery systems at an exit shear rate of between about 1 to 1×10−7 reciprocal second.
摘要翻译： 本发明涉及稳定的非水性单相粘性载体和利用这种载体的制剂。 制剂包含均匀悬浮在载体中的至少一种有益剂。 该制剂能够在从寒冷到体温的温度下长时间储存。 制剂能够以约1至1×10-7倒数第二次的出口剪切速率从药物递送系统均匀递送。
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