发明授权
- 专利标题： Method of diagnosing pancreatic cancer with the use of N-binding type sugar chains
- 专利标题（中）： 使用N-结合型糖链诊断胰腺癌的方法
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申请号： US12991340申请日： 2009-05-08
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公开(公告)号： US08372647B2公开(公告)日： 2013-02-12
- 发明人: Tokuzo Arao , Kazuko Matsumoto , Kazuto Nishio , Hiroki Sakamoto , Masayuki Kitano , Masatoshi Kudo
- 申请人： Tokuzo Arao , Kazuko Matsumoto , Kazuto Nishio , Hiroki Sakamoto , Masayuki Kitano , Masatoshi Kudo
- 申请人地址： JP Tokyo
- 专利权人： Sumitomo Bakelite Company Limited
- 当前专利权人： Sumitomo Bakelite Company Limited
- 当前专利权人地址： JP Tokyo
- 代理机构： King & Spalding
- 代理商 Kenneth H. Sonnenfeld; Margaret B. Brivanlou
- 优先权： JP2008-123391 20080509
- 国际申请： PCT/JP2009/002019 WO 20090508
- 国际公布： WO2009/136506 WO 20091112
- 主分类号： G01N33/48
- IPC分类号： G01N33/48 ; G01N24/00 ; C12Q1/34 ; C12Q1/37
摘要：
The present invention provides novel markers for diagnosing pancreatic cancer, and methods for determining if a subject has pancreatic cancer utilizing the markers, etc. The methods involve comparing mass-spectrometric peaks of certain sugar chains, obtained from patients' blood and determining if there is a significant decrease in peak intensity, compared with corresponding peaks from patients without pancreatic cancer.
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