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    Production method and a production system
    2.
    发明授权
    Production method and a production system 失效
    生产方式和生产系统

    公开(公告)号：US06862487B2

    公开(公告)日：2005-03-01

    申请号：US09852696

    申请日：2001-05-11

    申请人： Tomoharu Yamanaka ,  Yasuhiko Yamazaki ,  Masayuki Kitano

    发明人： Tomoharu Yamanaka ,  Yasuhiko Yamazaki ,  Masayuki Kitano

    IPC分类号： G06Q50/04 ,  B65G37/02 ,  G05B19/418 ,  G06Q50/00 ,  G06F19/00

    CPC分类号： B65G37/02 ,  Y02P90/04 ,  Y02P90/20

    摘要： Various models of brake parts (products) are produced with a mixedly transferring production system. The mixedly transferring production system includes a top line, a first production line, a second production line, and a third production line, a mixedly transferring depot, a part depot, and a set assembling line, and a product depot (mentioned in order of processing flow). Out of them, the first to third production lines, the mixedly transferring depot form the mixedly transferring block division type of production system. In addition, an averaging post and a production order plate (kanban) sorter are provided (mentioned in order of production command flow).

    摘要翻译： 各种型号的制动部件（产品）均采用混合转移生产系统生产。 混合转移生产系统包括顶线，第一生产线，第二生产线和第三生产线，混合转运仓库，部分仓库和组装生产线，以及产品仓库（按照 处理流程）。 其中，第一至第三条生产线，混合转运仓库形成了混合转移块分割型生产系统。 此外，还提供了平均化位置和生产订单板（看板）分类器（按照生产指令流程的顺序提供）。

    Method of Diagnosing Pancreatic Cancer with the Use of N-Binding Type Sugar Chains
    3.
    发明申请
    Method of Diagnosing Pancreatic Cancer with the Use of N-Binding Type Sugar Chains 失效
    使用N-结合型糖链诊断胰腺癌的方法

    公开(公告)号：US20110065141A1

    公开(公告)日：2011-03-17

    申请号：US12991340

    申请日：2009-05-08

    申请人： Tokuzo Arao ,  Kazuko Matsumoto ,  Kazuto Nishio ,  Hiroki Sakamoto ,  Masayuki Kitano ,  Masatoshi Kudo

    发明人： Tokuzo Arao ,  Kazuko Matsumoto ,  Kazuto Nishio ,  Hiroki Sakamoto ,  Masayuki Kitano ,  Masatoshi Kudo

    IPC分类号： C12Q1/37 ,  C12Q1/34

    CPC分类号： G01N33/57438 ,  Y10T436/24

    摘要： The present invention is to provide a novel marker for diagnosing pancreatic cancer, a method for determining if a subject has pancreatic cancer utilizing the marker, etc. The present inventors collected blood from patients of 78 cases in total including patients of 24 cases with pancreaticobiliary-duct benign disorder (16 gallstone cases and 8 pancreatitis cases) and patients of 54 cases with pancreatic cancer, and mass spectrometry was performed on N-linked sugar chains in plasma. From the 74 mass-spectrometric peaks detected, 65 sugar chains were extracted based on the results of PAM analysis. These extracted sugar chains were then used to predict pancreatic cancer or pancreaticobiliary-duct benign disorder, to correctly diagnose 74% cases. Further, a T-test was performed between the two groups, the group of pancreaticobiliary-duct benign disorder and the group of pancreatic cancer, which identified two sugar chains, the sugar chain of m/z 3031 and the sugar chain of m/z 2362, as sugar chains demonstrating significant difference (p

    摘要翻译： 本发明提供一种用于诊断胰腺癌的新型标记物，用于确定受试者是否使用标记物的胰腺癌的方法等。本发明人从78例患者中收集了总共包括24例胰腺胆管癌患者的血液， 膀胱良性疾病（16例胆囊病例和8例胰腺炎病例）和54例胰腺癌患者，并对血浆中的N链糖链进行质谱分析。 根据PAM分析结果，从检测到的74个质谱峰中提取出65个糖链。 然后将这些提取的糖链用于预测胰腺癌或胰胆管良性疾病，以正确诊断74％的病例。 此外，在两组之间进行T检验，即胰胆管良性病变组和胰腺癌组，鉴定了两条糖链，m / z 3031的糖链和m / z的糖链 2362，由于糖链显示出显着性差异（p <0.05），并且两组之间的表达水平呈现2倍或更大的差异。 使用这些糖链的正确检测率用六个分类器计算，所有这些分类器都得到约70％的正确检测结果。