发明授权
US08399204B2 Method for screening of substance which alter GPR120-mediated cell-stimulating activities
失效
筛选改变GPR120介导的细胞刺激活性的物质的方法
- 专利标题： Method for screening of substance which alter GPR120-mediated cell-stimulating activities
- 专利标题（中）： 筛选改变GPR120介导的细胞刺激活性的物质的方法
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申请号： US11991441申请日： 2006-09-01
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公开(公告)号： US08399204B2公开(公告)日： 2013-03-19
- 发明人: Tomoko Sekiya , Norimasa Miyamoto , Hirokazu Tanaka , Naoko Massaki
- 申请人： Tomoko Sekiya , Norimasa Miyamoto , Hirokazu Tanaka , Naoko Massaki
- 申请人地址： JP Tokyo-To
- 专利权人： Eisai R&D Management Co., Ltd.
- 当前专利权人： Eisai R&D Management Co., Ltd.
- 当前专利权人地址： JP Tokyo-To
- 代理机构： Clark & Elbing LLP
- 优先权： JP2005-254643 20050902
- 国际申请： PCT/JP2006/317331 WO 20060901
- 国际公布： WO2007/026874 WO 20070308
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; G01N33/567
摘要：
The present invention provides a screening method for determining whether a substance of interest is a substance which alters GPR120 mediated cell stimulating activities, comprising using a substance of interest, a biomembrane containing GPR120, or cells containing said biomembrane, and phospholipase or salts thereof. According to a screening method of the present invention, the method can screen substances such as CCK and GLP-1 which are involved in the secretion of hormones in gastrointestinal tracts.
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