发明授权
US08420647B2 4-phenoxy-nicotinamide or 4-phenoxy-pyrimidine-5-carboxamide compounds
失效
4-苯氧基 - 烟酰胺或4-苯氧基 - 嘧啶-5-甲酰胺化合物
- 专利标题： 4-phenoxy-nicotinamide or 4-phenoxy-pyrimidine-5-carboxamide compounds
- 专利标题（中）： 4-苯氧基 - 烟酰胺或4-苯氧基 - 嘧啶-5-甲酰胺化合物
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申请号： US13005566申请日： 2011-01-13
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公开(公告)号： US08420647B2公开(公告)日： 2013-04-16
- 发明人: Caterina Bissantz , Henrietta Dehmlow , Shawn David Erickson , Kyungjin Kim , Rainer E. Martin , Ulrike Obst Sander , Sherrie Lynn Pietranico-Cole , Hans Richter , Christoph Ulmer
- 申请人： Caterina Bissantz , Henrietta Dehmlow , Shawn David Erickson , Kyungjin Kim , Rainer E. Martin , Ulrike Obst Sander , Sherrie Lynn Pietranico-Cole , Hans Richter , Christoph Ulmer
- 申请人地址： US NJ Nutley
- 专利权人： Hoffmann-La Roche Inc.
- 当前专利权人： Hoffmann-La Roche Inc.
- 当前专利权人地址： US NJ Nutley
- 代理商 George W. Johnston; Patricia S. Rocha-Tramaloni; Gene J. Yao
- 优先权： EP10151319 20100121
- 主分类号： A61K31/498
- IPC分类号： A61K31/498
摘要：
This invention relates to novel phenyl amide or pyridyl amide derivatives of the formula wherein A1, A2, B1, B2 and R1 to R11 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and can be used as medicaments for the treatment of diseases such as type II diabetes.
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