发明授权
US08425845B2 Genetic analysis LOC with hybridization array with calibration chamber containing probe that lacks a reporter
失效
遗传分析具有杂交阵列的LOC，其中含有缺乏报告物的探针的校准室
- 专利标题： Genetic analysis LOC with hybridization array with calibration chamber containing probe that lacks a reporter
- 专利标题（中）： 遗传分析具有杂交阵列的LOC，其中含有缺乏报告物的探针的校准室
-
申请号： US13150184申请日： 2011-06-01
-
公开(公告)号： US08425845B2公开(公告)日： 2013-04-23
- 发明人: Kia Silverbrook , Mehdi Azimi
- 申请人： Kia Silverbrook , Mehdi Azimi
- 申请人地址： AU Rozelle, New South Wales
- 专利权人： Geneasys Pty Ltd
- 当前专利权人： Geneasys Pty Ltd
- 当前专利权人地址： AU Rozelle, New South Wales
- 主分类号： C40B40/04
- IPC分类号： C40B40/04 ; C40B40/06 ; C12M1/34 ; G01N21/64 ; C12Q1/68 ; G01N33/00 ; G01N1/00 ; G01N21/00 ; B01L3/00 ; C40B60/12
摘要：
A microfluidic device having a supporting substrate, an inlet for receiving a biological sample containing target nucleic acid sequences, hybridization chambers containing probes that each have a nucleic acid sequence for hybridization with the target nucleic acid sequences to form probe-target hybrids, a fluorophore and a quencher configured such that the fluorophore emits a fluorescence signal in response to an excitation light and the quencher quenches the fluorescence signal when the probe is not hybridized, but fails to quench the fluorescence signal from the probe-target hybrid, and, a calibration chamber with no fluorophore.
公开/授权文献
信息查询
