发明授权
US08426443B2 Compounds which have activity at M1 receptor and their uses in medicine
失效
具有M1受体活性的化合物及其在药物中的用途
- 专利标题： Compounds which have activity at M1 receptor and their uses in medicine
- 专利标题（中）： 具有M1受体活性的化合物及其在药物中的用途
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申请号： US13592785申请日： 2012-08-23
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公开(公告)号： US08426443B2公开(公告)日： 2013-04-23
- 发明人: David Gwyn Cooper , Ian Thomson Forbes , Vincenzo Garzya , Dale James Johnson , Graeme Irvine Stevenson , Paul Adrian Wyman
- 申请人： David Gwyn Cooper , Ian Thomson Forbes , Vincenzo Garzya , Dale James Johnson , Graeme Irvine Stevenson , Paul Adrian Wyman
- 申请人地址： GB Greenford, Middlesex
- 专利权人： Glaxo Group Limited
- 当前专利权人： Glaxo Group Limited
- 当前专利权人地址： GB Greenford, Middlesex
- 代理商 Linda E. Hall; John L. Lemanowicz
- 主分类号： A61K31/445
- IPC分类号： A61K31/445 ; A61K31/425 ; A61K31/42
摘要：
Compounds of formula (I) or a salt thereof are provided: wherein R4, R5, R6, Q, A, Y and R are as defined in the description. Uses of the compounds as medicaments and in the manufacture of medicaments for treating psychotic disorders, cognitive impairments and Alzheimer's Disease are disclosed. The invention further discloses pharmaceutical compositions comprising the compounds.
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