Invention Grant
- Patent Title: Triazoles as inhibitors of fatty acid synthase
- Patent Title (中): 三唑作为脂肪酸合酶的抑制剂
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Application No.: US13101970Application Date: 2011-05-05
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Publication No.: US08450350B2Publication Date: 2013-05-28
- Inventor: Adilah Bahadoor , Alfredo C. Castro , Lawrence K. Chan , Gregg F. Keaney , Marta Nevalainen , Vesa Nevalainen , Stephane Peluso , Thomas T. Tibbitts
- Applicant: Adilah Bahadoor , Alfredo C. Castro , Lawrence K. Chan , Gregg F. Keaney , Marta Nevalainen , Vesa Nevalainen , Stephane Peluso , Thomas T. Tibbitts
- Applicant Address: US MA Cambridge
- Assignee: Infinity Pharmaceuticals, Inc.
- Current Assignee: Infinity Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Jones Day
- Main IPC: A61K31/41
- IPC: A61K31/41 ; A61K31/4192 ; C07D249/00 ; C07D249/06
Abstract:
Provided herein are triazole FASN inhibitors of the formula (I): or a pharmaceutically acceptable form thereof; wherein the variables RA, X, RB, and RC are defined herein. Also provided herein are pharmaceutical compositions of the compounds provided herein as well as methods of their use for the treatment of various disorders such as hyperproliferative disorders, inflammatory disorders, obesity-related disorders and microbial infections.
Public/Granted literature
- US20110274654A1 TRIAZOLES AS INHIBITORS OF FATTY ACID SYNTHASE Public/Granted day:2011-11-10
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