发明授权
- 专利标题: Compounds for the treatment of inflammatory diseases
- 专利标题(中): 用于治疗炎性疾病的化合物
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申请号: US13120730申请日: 2009-09-22
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公开(公告)号: US08450355B2公开(公告)日: 2013-05-28
- 发明人: Michael K. C. Wong , Wensheng Yu , Ling Tong , Brian J. Lavey , Bandarpalle B. Shankar , Joseph A. Kozlowski , Seong Heon Kim , Guowei Zhou , De-Yi Yang , Razia K. Rizvi , Lei Chen , Aneta Maria Kosinzki , Kristin E. Rosner , Luke Fire , Judson E. Richard , Dansu Li
- 申请人: Michael K. C. Wong , Wensheng Yu , Ling Tong , Brian J. Lavey , Bandarpalle B. Shankar , Joseph A. Kozlowski , Seong Heon Kim , Guowei Zhou , De-Yi Yang , Razia K. Rizvi , Lei Chen , Aneta Maria Kosinzki , Kristin E. Rosner , Luke Fire , Judson E. Richard , Dansu Li
- 申请人地址: US NJ Rahway
- 专利权人: Merck Sharp & Dohme Corp.
- 当前专利权人: Merck Sharp & Dohme Corp.
- 当前专利权人地址: US NJ Rahway
- 代理商 Eric A. Meade; Valerie J. Camara
- 国际申请: PCT/US2009/057805 WO 20090922
- 国际公布: WO2010/036640 WO 20100401
- 主分类号: A61K31/4166
- IPC分类号: A61K31/4166 ; A61K31/4178 ; C07D233/02
摘要:
This invention relates to compounds of the Formula (I)-(IX):, as defined herein, or a pharmaceutically acceptable salt, solvate or ester thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF-α combinations thereof.
公开/授权文献
- US20110288077A1 COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES 公开/授权日:2011-11-24
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