- 专利标题： Variant target binding agents and uses thereof
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申请号： US12516914申请日： 2007-12-01
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公开(公告)号： US08455622B2公开(公告)日： 2013-06-04
- 发明人: Charlotte McDonagh , Paul Carter , Django Sussman
- 申请人： Charlotte McDonagh , Paul Carter , Django Sussman
- 申请人地址： US WA Bothell
- 专利权人： Seattle Genetics, Inc.
- 当前专利权人： Seattle Genetics, Inc.
- 当前专利权人地址： US WA Bothell
- 代理商 Leslie E. Aberman
- 国际申请： PCT/US2007/086205 WO 20071201
- 国际公布： WO2008/070593 WO 20080612
- 主分类号： C07K16/00
- IPC分类号： C07K16/00 ; C12P21/08 ; A61K39/395 ; A61K39/40 ; A61K39/00 ; C07K1/00
摘要：
The present invention provides variant target binding agents and methods relating to the use of such binding agents for the prophylaxis or treatment of cancers and immunological disorders. The variant target binding agent is conjugated to a therapeutic agent that exerts a cytotoxic, cytostatic, or immunomodulatory effect on target cells.
公开/授权文献
- US20100158909A1 Variant Target Binding Agents and Uses Thereof 公开/授权日：2010-06-24