发明授权
- 专利标题: Compounds
- 专利标题(中): 化合物
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申请号: US13314565申请日: 2011-12-08
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公开(公告)号: US08466186B2公开(公告)日: 2013-06-18
- 发明人: Henning Priepke , Raimund Kuelzer , Juergen Mack , Roland Pfau , Dirk Stenkamp , Benjamin Pelcman , Robert Roenn , Dimitrijs Lubriks , Edgars Suna
- 申请人: Henning Priepke , Raimund Kuelzer , Juergen Mack , Roland Pfau , Dirk Stenkamp , Benjamin Pelcman , Robert Roenn , Dimitrijs Lubriks , Edgars Suna
- 申请人地址: DE Ingelheim am Rhein
- 专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人: Boehringer Ingelheim International GmbH
- 当前专利权人地址: DE Ingelheim am Rhein
- 代理商 Michael P. Morris; Philip I. Datlow
- 优先权: EP10194456 20101210
- 主分类号: A01N43/52
- IPC分类号: A01N43/52 ; A01N33/02 ; A01N33/18 ; A61K31/135 ; A61K31/04
摘要:
This invention relates to compounds of formula I their use as inhibitors of the microsomal prostaglandin E2 synthase-1 (mPGES-1), to pharmaceutical compositions containing them, and their use as medicaments for the treatment and/or prevention of inflammatory diseases and associated conditions. A, M, W, R1, R2, R3, R4, R6, R2, R7, R8, R9, Ra, Rb have meanings given in the description.
公开/授权文献
- US20120309738A1 NOVEL COMPOUNDS 公开/授权日:2012-12-06
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