Invention Grant
- Patent Title: Production of high levels of DHA in microalgae using modified amounts of chloride and potassium
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Application No.: US13762324Application Date: 2013-02-07
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Publication No.: US08497099B2Publication Date: 2013-07-30
- Inventor: Paul W. Behrens , John M. Thompson , Kirk Apt , Joseph W. Pfeifer, III , James P. Wynn , James Casey Lippmeier , Jaouad Fichtali , Jon Hansen
- Applicant: DSM IP Assets B.V.
- Applicant Address: NL Heerlen
- Assignee: DSM IP Assets B.V.
- Current Assignee: DSM IP Assets B.V.
- Current Assignee Address: NL Heerlen
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Main IPC: C12P7/64
- IPC: C12P7/64 ; C12N1/12 ; C11B1/00 ; A23D9/02 ; A23L1/30

Abstract:
Methods for production of highly unsaturated fatty acids by marine microorganisms, including the heterotrophic marine dinoflagellate Crypthecodinium, using low levels of chloride ion are disclosed. Specifically, methods of increasing production of highly unsaturated fatty acids by marine microorganisms while growing in low chloride media by manipulating sodium ion and potassium ion levels. The invention also relates to methods of production of highly unsaturated fatty acids by marine organisms at low pH levels, and includes methods for generation of low pH tolerant strains.
Public/Granted literature
- US08669090B2 Production of high levels of DHA in microalgae using modified amounts of chloride and potassium Public/Granted day:2014-03-11
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