发明授权
US08501464B2 Lentiviral vectors carrying synthetic bi-directional promoters and uses thereof
有权
携带合成双向启动子的慢病毒载体及其用途
- 专利标题: Lentiviral vectors carrying synthetic bi-directional promoters and uses thereof
- 专利标题(中): 携带合成双向启动子的慢病毒载体及其用途
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申请号: US10554181申请日: 2004-04-21
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公开(公告)号: US08501464B2公开(公告)日: 2013-08-06
- 发明人: Luigi Naldini , Mario Amendola , Elisa Vigna
- 申请人: Luigi Naldini , Mario Amendola , Elisa Vigna
- 申请人地址: IT Milan
- 专利权人: Ospedale San Raffaele S.r.l.
- 当前专利权人: Ospedale San Raffaele S.r.l.
- 当前专利权人地址: IT Milan
- 代理机构: Lucas & Mercanti, LLP
- 国际申请: PCT/IT2004/000227 WO 20040421
- 国际公布: WO2004/094642 WO 20041104
- 主分类号: C12N15/00
- IPC分类号: C12N15/00 ; C12P21/06 ; C12P21/04 ; C12N15/74 ; C12P21/00
摘要:
It is described a bidirectional promoter for expression of at least two coding sequences in opposite direction in animal cells; bidirectional expression cassettes; expression constructs; gene transfer expression vectors, and methods for the use thereof.