发明授权
- 专利标题： Potassium channel blockers and uses thereof
- 专利标题（中）： 钾通道阻滞剂及其用途
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申请号： US12997864申请日： 2009-06-12
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公开(公告)号： US08507539B2公开(公告)日： 2013-08-13
- 发明人: Andrew John Harvey , Bernard Luke Flynn , Jorgen Alvar Mould , Dharam Paul , Gurmit Singh Gill , Justin Anthony Ripper , Rachel Christine Cooke , Julia Stephanie Crossman , Jonathan Bayldon Baell , Nathan Wayne Kuchel , Rajinder Singh
- 申请人： Andrew John Harvey , Bernard Luke Flynn , Jorgen Alvar Mould , Dharam Paul , Gurmit Singh Gill , Justin Anthony Ripper , Rachel Christine Cooke , Julia Stephanie Crossman , Jonathan Bayldon Baell , Nathan Wayne Kuchel , Rajinder Singh
- 申请人地址： AU Thebarton, South Austrialia
- 专利权人： Bionomics Limited
- 当前专利权人： Bionomics Limited
- 当前专利权人地址： AU Thebarton, South Austrialia
- 代理机构： Knobbe, Martens, Olson & Bear, LLP
- 国际申请： PCT/AU2009/000739 WO 20090612
- 国际公布： WO2009/149508 WO 20091217
- 主分类号： A61K31/423
- IPC分类号： A61K31/423 ; C07D263/54
摘要：
The present invention relates to compounds useful in the modulation of potassium channel activity in cells, in particular the activity of Kv1.3 channels found in T cells. The invention also relates to the use of these compounds in the treatment or prevention of autoimmune and inflammatory diseases, including multiple sclerosis, pharmaceutical compositions containing these compounds and methods for their preparation.
公开/授权文献
- US20110166130A1 NOVEL POTASSIUM CHANNEL BLOCKERS AND USES THEREOF 公开/授权日：2011-07-07