发明授权
US08512949B2 Diagnosis/treatment option for head-and-neck tumor using micro-RNA as biomarker
有权
使用微RNA作为生物标志物的头颈部肿瘤的诊断/治疗选择
- 专利标题： Diagnosis/treatment option for head-and-neck tumor using micro-RNA as biomarker
- 专利标题（中）： 使用微RNA作为生物标志物的头颈部肿瘤的诊断/治疗选择
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申请号： US12996420申请日： 2009-06-10
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公开(公告)号： US08512949B2公开(公告)日： 2013-08-20
- 发明人: Takeru Zama , Koichiro Saito , Akira Hirasawa , Hideki Naganishi
- 申请人： Takeru Zama , Koichiro Saito , Akira Hirasawa , Hideki Naganishi
- 申请人地址： JP Tokyo JP Tokyo
- 专利权人： Takeru Zama,Koichiro Saito
- 当前专利权人： Takeru Zama,Koichiro Saito
- 当前专利权人地址： JP Tokyo JP Tokyo
- 代理机构： King & Spalding LLP
- 代理商 Kenneth H. Sonnenfeld; Margaret B. Brivanlou
- 优先权： JP2008-154547 20080612; JP2008-243306 20080922; JP2009-099849 20090416
- 国际申请： PCT/JP2009/002629 WO 20090610
- 国际公布： WO2009/150839 WO 20091217
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
Disclosed are: a method for using a particular microRNA as a biomarker for head-and-neck tumor; a method for the determination of head-and-neck tumor; a kit for the determination of head-and-neck tumor, and the like. The present invention is characterized in that at least one microRNA selected from the group of microRNAs consisting of miR-455-3p, miR-455-5p, miR-130b, miR-130b*, miR-801, miR-196a, miR-21, miR-31, miR-133b, miR-145 and miR-375 is used as a biomarker for head-and-neck tumor.
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