发明授权
US08524872B2 Nucleic acids and corresponding proteins entitled 158P3D2 useful in treatment and detection of cancer
失效
题为158P3D2的核酸和相应的蛋白质可用于治疗和检测癌症
- 专利标题： Nucleic acids and corresponding proteins entitled 158P3D2 useful in treatment and detection of cancer
- 专利标题（中）： 题为158P3D2的核酸和相应的蛋白质可用于治疗和检测癌症
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申请号： US13481637申请日： 2012-05-25
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公开(公告)号： US08524872B2公开(公告)日： 2013-09-03
- 发明人: Arthur B. Raitano , Aya Jakobovits , Pia M. Challita-Eid , Steven B. Kanner , Wangmao Ge , Juan J. Perez-Villar , Robert Kendall Morrison
- 申请人： Arthur B. Raitano , Aya Jakobovits , Pia M. Challita-Eid , Steven B. Kanner , Wangmao Ge , Juan J. Perez-Villar , Robert Kendall Morrison
- 申请人地址： US CA Santa Monica
- 专利权人： Agensys, Inc.
- 当前专利权人： Agensys, Inc.
- 当前专利权人地址： US CA Santa Monica
- 代理机构： Morrison & Foerster LLP
- 主分类号： C07K14/00
- IPC分类号： C07K14/00
摘要：
A novel gene 158P3D2 and its encoded protein, and variants thereof, are described wherein 158P3D2 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 158P3D2 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 158P3D2 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 158P3D2 can be used in active or passive immunization.
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