Invention Grant
- Patent Title: Process for the preparation of oxcarbazepine
- Patent Title (中): 奥卡西平制备方法
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Application No.: US12991600Application Date: 2009-05-06
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Publication No.: US08530647B2Publication Date: 2013-09-10
- Inventor: Nageswara Rao Karusala , Uma Sankara Sastry Tummalapally , Appi Reddy Talatala , Debashish Datta
- Applicant: Nageswara Rao Karusala , Uma Sankara Sastry Tummalapally , Appi Reddy Talatala , Debashish Datta
- Applicant Address: IN
- Assignee: Mylan Laboratories Limited
- Current Assignee: Mylan Laboratories Limited
- Current Assignee Address: IN
- Agency: Lerner, David, Littenberg, Krumholz & Mentlik, LLP
- Priority: IN1135/CHE/2008 20080508; IN1678/CHE/2008 20080710
- International Application: PCT/IN2009/000272 WO 20090506
- International Announcement: WO2009/139001 WO 20091119
- Main IPC: C07D223/26
- IPC: C07D223/26
Abstract:
The present invention relates to an improved process for the preparation of 10-oxo-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide (Oxcarbazepine) by reacting 10-methoxy-5H-dibenz[b,f]azepine (10-methoxyiminostilbene) and alkali metal cyanate in presence of α-hydroxy acids, and also relates to the process for the preparation of carbamazepine from iminostilbene. Further the present invention is directed to the novel crystalline form of 10-methoxy carbamazepine.
Public/Granted literature
- US20110065917A1 PROCESS FOR THE PREPARATION OF OXCARBAZEPINE Public/Granted day:2011-03-17
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