发明授权
US08541376B2 Composition comprising and method of using angiopoietin-like protein 3 ANGPTL3
有权
组合物和使用血管生成素样蛋白3 ANGPTL3的方法
- 专利标题： Composition comprising and method of using angiopoietin-like protein 3 ANGPTL3
- 专利标题（中）： 组合物和使用血管生成素样蛋白3 ANGPTL3的方法
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申请号： US12128545申请日： 2008-05-28
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公开(公告)号： US08541376B2公开(公告)日： 2013-09-24
- 发明人: Napoleone Ferrara , Hans-Peter Gerber , Joe Kowalski , Maria Teresa Pisabarro , Daniel Eric Sherman
- 申请人： Napoleone Ferrara , Hans-Peter Gerber , Joe Kowalski , Maria Teresa Pisabarro , Daniel Eric Sherman
- 申请人地址： US CA South San Francisco
- 专利权人： Genentech, Inc.
- 当前专利权人： Genentech, Inc.
- 当前专利权人地址： US CA South San Francisco
- 代理机构： Morrison & Foerster LLP
- 主分类号： A61K38/16
- IPC分类号： A61K38/16 ; A61K38/10 ; A61K39/00
摘要：
The present invention is directed to methods and means for making and using Angptl3 polypeptides. The invention specifically concerns the use of Angptl3 polypeptides in inducing liver regeneration and angiogenesis. Further methods include the use of Angptl3 polypeptides in the diagnosis and treatment of liver disease. Also provided herein are antibodies which bind to the polypeptides of the present invention.
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