Invention Grant
- Patent Title: Heterocyclic derivatives, pharmaceutical compositions and methods of use thereof
- Patent Title (中): 杂环衍生物，药物组合物及其使用方法
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Application No.: US12438291Application Date: 2006-08-22
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Publication No.: US08541428B2Publication Date: 2013-09-24
- Inventor: Moshe Gavish , Jehuda Arieh Veenman , Alex Shterenberg , Ilan Marek
- Applicant: Moshe Gavish , Jehuda Arieh Veenman , Alex Shterenberg , Ilan Marek
- Applicant Address: IL Technion, Haifa
- Assignee: Technion Research and Development Foundation Ltd.
- Current Assignee: Technion Research and Development Foundation Ltd.
- Current Assignee Address: IL Technion, Haifa
- Agency: Browdy and Neimark, PLLC.
- International Application: PCT/IL2006/000979 WO 20060822
- International Announcement: WO2008/023357 WO 20080228
- Main IPC: A01N43/54
- IPC: A01N43/54 ; A61K31/517 ; C07D239/72
Abstract:
The present invention relates to novel quinoxaline, quinazoline and phthalazine derivatives as well as multimeric derivatives, methods for their preparation, pharmaceutical compositions including such compounds, and methods of using these compounds for the treatment and prevention of brain damage resulting from brain injury, especially secondary brain damage due to traumatic brain injury (TBI). The compounds of the invention are also useful in treating and preventing neurodegenerative diseases.
Public/Granted literature
- US20100029658A1 HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF Public/Granted day:2010-02-04
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