Invention Grant
- Patent Title: Modulators of ATP-binding cassette transporters
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Application No.: US13112115Application Date: 2011-05-20
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Publication No.: US08541453B2Publication Date: 2013-09-24
- Inventor: Sara Sabina Hadida-Ruah , Peter Diederik Jan Grootenhuis , Mark Thomas Miller , Matthew Hamilton
- Applicant: Sara Sabina Hadida-Ruah , Peter Diederik Jan Grootenhuis , Mark Thomas Miller , Matthew Hamilton
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Cambridge
- Agent Michael J. DiVerdi
- Main IPC: C07D231/40
- IPC: C07D231/40 ; C07D233/88 ; C07D263/48 ; C07D271/113 ; C07D277/46 ; C07D277/54 ; C07D277/82 ; C07D285/135 ; C07D405/12 ; C07D407/12 ; C07D409/12 ; C07D409/14 ; C07D413/12 ; C07D417/04 ; C07D417/06 ; C07D417/12 ; C07D417/14 ; C07D493/10 ; A61K31/454 ; A61K31/427 ; A61K31/4439 ; A61K31/433 ; A61K31/4245 ; A61K31/4178 ; A61K31/422 ; A61P11/00 ; A61P3/00 ; A61P3/06 ; A61P3/10 ; A61P25/28 ; A61P25/00 ; A61P1/12 ; A61P27/02 ; A61P13/12
Abstract:
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
Public/Granted literature
- US20110306637A1 MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS Public/Granted day:2011-12-15
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