发明授权
- 专利标题： Kit comprising elastase
- 专利标题（中）： 试剂盒包含弹性蛋白酶
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申请号： US11454554申请日： 2006-06-16
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公开(公告)号： US08568716B2公开(公告)日： 2013-10-29
- 发明人: F. Nicholas Franano
- 申请人： F. Nicholas Franano
- 申请人地址： US MA Waltham
- 专利权人： Proteon Therapeutics, Inc.
- 当前专利权人： Proteon Therapeutics, Inc.
- 当前专利权人地址： US MA Waltham
- 代理机构： Fried, Frank, Harris, Shriver & Jacobson LLP
- 主分类号： A61K38/46
- IPC分类号： A61K38/46 ; A61K38/48 ; A61K38/55 ; A61K35/39 ; C12Q1/34 ; C12Q1/37 ; A61M25/06 ; A61M29/02 ; A61M31/00 ; A61M25/085 ; A61M25/10 ; A61M29/00
摘要：
The invention provides methods for treating an obstructed biological conduit that include administering to the conduit an agent that can degrade extracellular matrix of obstructing tissue. Particular methods include delivery of an enzyme or a mixture of several enzymes to the area or region of obstruction wherein the enzyme(s) have the capability to degrade extracellular matrix components within the obstruction thereby restoring the normal flow of transported fluid through the conduit. The invention also includes prophylactically dilating a section of conduit to minimize the risk of obstruction formation.
公开/授权文献
- US20070014782A1 Systems for enlarging the diameter of an artery or vein 公开/授权日：2007-01-18