发明授权
US08569312B2 Biaryl-spiroaminooxzaoline analogues as alpha 2C adrenergic receptor modulators
失效
双芳基 - 螺氨基氧杂环丁烷类似物作为α2C肾上腺素能受体调节剂
- 专利标题： Biaryl-spiroaminooxzaoline analogues as alpha 2C adrenergic receptor modulators
- 专利标题（中）： 双芳基 - 螺氨基氧杂环丁烷类似物作为α2C肾上腺素能受体调节剂
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申请号： US13857001申请日： 2013-04-04
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公开(公告)号： US08569312B2公开(公告)日： 2013-10-29
- 发明人: Kevin D. McCormick , Li Dong , Christopher W. Boyce , Manuel de Lera Ruiz , Salem Fevrier , Jie Wu , Junying Zheng , Younong Yu , Jianhua Chao , Walter S. Won , Ashwin U. Rao , Rongze Kuang , Pauline C. Ting , Xianhai Huang , Ning Shao , Anandan Palani , Michael Y. Berlin , Robert G. Aslanian
- 申请人： Merck Sharp & Dohme Corp.
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 代理商 H. Eric Fischer; Gerard M. Devlin
- 主分类号： A61K31/506
- IPC分类号： A61K31/506 ; A61K31/501 ; A61K31/4439 ; A61K31/497 ; A61K31/4184 ; C07D235/02 ; C07D405/10 ; C07D409/10 ; C07D403/10
摘要：
In its many embodiments, the present invention provides a novel class of biaryl spiroaminooxazoline analogues as modulators of α2C adrenergic receptor agonists, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more conditions associated with the α2C adrenergic receptors using such compounds or pharmaceutical compositions.
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