Invention Grant
- Patent Title: Intermediate and process for preparing entecavir using same
- Patent Title (中): 使用相同方法制备恩替卡韦的中间体和方法
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Application No.: US13140640Application Date: 2009-12-24
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Publication No.: US08569490B2Publication Date: 2013-10-29
- Inventor: Jaeheon Lee , Gha-Seung Park , Jin Hee Kim , Ji Eun Lee , Chul Hyun Park , Tae Jin Choi , Eun-Ju Park , Cheol Kyung Kim , Eun Jung Lim , Young-Kil Chang , Gwan Sun Lee
- Applicant: Jaeheon Lee , Gha-Seung Park , Jin Hee Kim , Ji Eun Lee , Chul Hyun Park , Tae Jin Choi , Eun-Ju Park , Cheol Kyung Kim , Eun Jung Lim , Young-Kil Chang , Gwan Sun Lee
- Applicant Address: KR Hwaseong-si
- Assignee: Hanmi Science Co., Ltd
- Current Assignee: Hanmi Science Co., Ltd
- Current Assignee Address: KR Hwaseong-si
- Agency: Sughrue Mion, PLLC
- Priority: KR10-2008-0134756 20081226
- International Application: PCT/KR2009/007786 WO 20091224
- International Announcement: WO2010/074534 WO 20100701
- Main IPC: C07D473/18
- IPC: C07D473/18 ; C07F7/08 ; C07C49/517
Abstract:
The present invention relates to a novel, high-yield and low-cost method for preparing entecavir, [1-S-(1α,3α,4β)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one, an antiviral agent, and novel intermediates used therein.
Public/Granted literature
- US20110251387A1 NOVEL INTERMEDIATE AND PROCESS FOR PREPARING ENTECAVIR USING SAME Public/Granted day:2011-10-13
Information query
