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21 条记录 (耗时 0.016 秒)

    1-Alpha-Halo-2,2-Difluoro-2-Deoxy-D-Ribofuranose Derivatives and Process for the Preparation Thereof
    6.
    发明申请
    1-Alpha-Halo-2,2-Difluoro-2-Deoxy-D-Ribofuranose Derivatives and Process for the Preparation Thereof 失效
    1-α-卤代-2,2-二氟-2-脱氧-D-呋喃核糖衍生物及其制备方法

    公开(公告)号：US20070238865A1

    公开(公告)日：2007-10-11

    申请号：US11572790

    申请日：2005-06-21

    申请人： Jaeheon Lee ,  Gha Park ,  Moonsub Lee ,  Han Kim ,  Hyo-Jeong Bang ,  Young-Kil Chang ,  Gwan Lee

    发明人： Jaeheon Lee ,  Gha Park ,  Moonsub Lee ,  Han Kim ,  Hyo-Jeong Bang ,  Young-Kil Chang ,  Gwan Lee

    IPC分类号： C07H15/00

    CPC分类号： C07H3/08

    摘要： 1-α-halo-2,2-difluoro-2-deoxy-D-ribofuranose derivative of formula (I) having the 3-hydroxy group protected with a biphenylcarbonyl group is a solid which can be easily purified by a simple procedure such as recrystallization, and therefore, it can be advantageously used as an intermediate in the preparation of gemcitabine in a large scale. Further, the 1-α-halo-2,2-difluoro-2-deoxy-D-ribofuranose derivative of formula (I) can be prepared with high stereoselectivity using the compound of formula (V) as an intermediate.

    摘要翻译： 具有用联苯基羰基保护的3-羟基的式（I）的1-α-卤代-2,2-二氟-2-脱氧-D-呋喃核糖衍生物是可以通过简单的方法容易地纯化的固体，例如 重结晶，因此可以有利地用作大量制备吉西他滨的中间体。 此外，式（I）的1-α-卤代-2,2-二氟-2-脱氧-D-呋喃核糖衍生物可以使用式（V）化合物作为中间体以高立体选择性制备。

    Cooling device and insert for water jacket of internal combustion engine
    9.
    发明授权
    Cooling device and insert for water jacket of internal combustion engine 有权
    内燃机水套冷却装置及插件

    公开(公告)号：US08689744B2

    公开(公告)日：2014-04-08

    申请号：US12507392

    申请日：2009-07-22

    申请人： Dongsuk Chae ,  Kwangsik Yang ,  Taewon Park ,  Wootae Kim ,  Sanghee Lee ,  Jaeheon Lee ,  Changseok Oh ,  Kiwoong Song

    发明人： Dongsuk Chae ,  Kwangsik Yang ,  Taewon Park ,  Wootae Kim ,  Sanghee Lee ,  Jaeheon Lee ,  Changseok Oh ,  Kiwoong Song

    IPC分类号： F02F1/14

    CPC分类号： F01P3/02 ,  F02F1/108 ,  F02F1/14

    摘要： The present invention is provided with one or more inserts that are inserted at the lower portion of a water jacket formed at siamese portions between cylinder bores of a cylinder block and increase the flow of cooling water at the upper portion of the water jacket, in order to provide a cooling device and an insert for a water jacket of an internal combustion engine, which is inserted at the lower portion of the water jacket formed at the siamese portions of the cylinder block to increase the flow of cooling water, improves cooling efficiency of the siamese portions of the cylinder block by inducting recirculation of the cooling water at the lower portion, and improves fuel efficiency by making the temperature uniform in the stroke direction of the piston of the cylinder block and reducing friction of the piston.

    摘要翻译： 本发明提供了一个或多个插入件，其插入在气缸体的气缸孔之间形成在暹罗部分处的水套的下部，并按顺序增加水套上部的冷却水流量 提供一种内燃机的水套的冷却装置和插入件，其插入形成在气缸体的暹粒部分处的水套的下部，以增加冷却水的流动，​​从而提高冷却水的冷却效率 通过在下部引入冷却水的再循环，从而使气缸体的活塞的行程方向上的温度均匀，降低活塞的摩擦，提高燃料效率，从而提高燃油效率。