Invention Grant
- Patent Title: SGLT-2 inhibitors, methods of making them, and uses thereof
- Patent Title (中): SGLT-2抑制剂，其制备方法及其应用
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Application No.: US13052171Application Date: 2011-03-21
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Publication No.: US08575114B2Publication Date: 2013-11-05
- Inventor: Shuang Liu , Cheng Guo
- Applicant: Shuang Liu , Cheng Guo
- Applicant Address: US NY Albany
- Assignee: Albany Molecular Research, Inc.
- Current Assignee: Albany Molecular Research, Inc.
- Current Assignee Address: US NY Albany
- Agency: LeClairRyan, a Professional Corporation
- Main IPC: A01N43/04
- IPC: A01N43/04 ; A61K31/70 ; C07H5/04 ; C07H5/06
Abstract:
The present invention relates to compounds which are inhibitors of sodium dependent glucose co-transporter-2 (SGLT-2). These compounds are used in the treatment of various disorders, including diabetes, impaired glucose tolerance, insulin resistance, retinopathy, nephropathy, neuropathy, cataracts, hyperglycemia, hyperinsulinemia, hyperchlolesterolemia, elevated blood level of free fatty acids or glycerol, hyperlipidemia, hypertriglyceridemia, obesity, wound healing, tissue ischemia, atherosclerosis, and hypertension. These compounds and compositions are also useful for treating and preventing kidney stones, hyperuricemia, gout, and hyponatremia. Methods of making these compounds are also described in the present invention.
Public/Granted literature
- US20110237527A1 SGLT-2 INHIBITORS, METHODS OF MAKING THEM, AND USES THEREOF Public/Granted day:2011-09-29
Information query
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