Invention Grant
US08580749B2 Peptide-coated cell localization to diseased or damaged tissues and methods related thereto
有权
患有病变或受损组织的肽包被细胞定位及其相关方法
- Patent Title: Peptide-coated cell localization to diseased or damaged tissues and methods related thereto
- Patent Title (中): 患有病变或受损组织的肽包被细胞定位及其相关方法
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Application No.: US12795195Application Date: 2010-06-07
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Publication No.: US08580749B2Publication Date: 2013-11-12
- Inventor: Joseph Wagner , Randell Young , David Fink
- Applicant: Joseph Wagner , Randell Young , David Fink
- Applicant Address: US CA Alameda
- Assignee: Cell Targeting, Inc.
- Current Assignee: Cell Targeting, Inc.
- Current Assignee Address: US CA Alameda
- Agent E. Stewart Mittler
- Main IPC: A61K38/08
- IPC: A61K38/08
Abstract:
Embodiments of the present invention are directed to a coated cell comprising a therapeutic cell and a plurality of targeting complexes coating the therapeutic cell and each of said targeting complexes comprising a homing molecule, a lipid moiety, and a spacer having from about 1 to about 10 amino acids and covalently linking the homing molecule to the lipid moiety and wherein the lipid moiety is non-covalently attached to the therapeutic cell. In some embodiments, the therapeutic cell is a stem cell. Embodiments of the invention are directed to methods of coating a therapeutic cell. Embodiments of the invention are directed to methods of treating diseases of the vasculature.
Public/Granted literature
- US20100310531A1 PEPTIDE-COATED CELL LOCALIZATION TO DISEASED OR DAMAGED TISSUES AND METHODS RELATED THERETO Public/Granted day:2010-12-09
Information query
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