发明授权
US08586550B2 Thiazole derivatives as SGLT2 inhibitors and pharmaceutical composition comprising same
有权
作为SGLT2抑制剂的噻唑衍生物和包含其的药物组合物
- 专利标题: Thiazole derivatives as SGLT2 inhibitors and pharmaceutical composition comprising same
- 专利标题(中): 作为SGLT2抑制剂的噻唑衍生物和包含其的药物组合物
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申请号: US13704081申请日: 2011-06-10
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公开(公告)号: US08586550B2公开(公告)日: 2013-11-19
- 发明人: Jinhwa Lee , Jeongmin Kim , Suk Ho Lee , Junwon Lee , Kwang-Seop Song , Eun-Jung Park , Min Ju Kim , Hee Jeong Seo , Sung-Han Lee , Eun Jung Son , Jong Yup Kim , Suk Youn Kang , Younggyu Kong
- 申请人: Jinhwa Lee , Jeongmin Kim , Suk Ho Lee , Junwon Lee , Kwang-Seop Song , Eun-Jung Park , Min Ju Kim , Hee Jeong Seo , Sung-Han Lee , Eun Jung Son , Jong Yup Kim , Suk Youn Kang , Younggyu Kong
- 申请人地址: KR Yongin-Si, Gyeonggi-Do
- 专利权人: Green Cross Corporation
- 当前专利权人: Green Cross Corporation
- 当前专利权人地址: KR Yongin-Si, Gyeonggi-Do
- 代理机构: Alston & Bird LLP
- 国际申请: PCT/KR2011/004273 WO 20110610
- 国际公布: WO2011/159067 WO 20111222
- 主分类号: A61K31/70
- IPC分类号: A61K31/70 ; A61K31/425 ; C07H5/04 ; C07H5/06 ; C07D277/60
摘要:
The present invention relates to a novel compound with thiazole ring having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney, and a pharmaceutical composition comprising the same as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly diabetes.
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