Invention Grant
US08592578B2 Process for preparing 2-(aminomethylidene)-4,4-difluoro-3-oxobutyric esters
有权
制备2-(氨基亚甲基)-4,4-二氟-3-氧代丁酸酯的方法
- Patent Title: Process for preparing 2-(aminomethylidene)-4,4-difluoro-3-oxobutyric esters
- Patent Title (中): 制备2-(氨基亚甲基)-4,4-二氟-3-氧代丁酸酯的方法
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Application No.: US13653615Application Date: 2012-10-17
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Publication No.: US08592578B2Publication Date: 2013-11-26
- Inventor: Thomas Zierke , Volker Maywald , Michael Rack , Sebastian Peer Smidt , Michael Keil , Bernd Wolf , Christopher Koradin
- Applicant: BASF SE
- Applicant Address: DE Lugwigshafen
- Assignee: BASF SE
- Current Assignee: BASF SE
- Current Assignee Address: DE Lugwigshafen
- Agency: Brinks Gilson & Lione
- Priority: EP08155612 20080502
- Main IPC: C07D231/14
- IPC: C07D231/14 ; C07D265/30 ; C07D295/145

Abstract:
The present invention relates to a process for preparing difluoromethyl-substituted pyrazol-4-ylcarboxylic acids and their esters, 2-(aminomethylidene)-4,4-difluoro-3-oxobutteric esters of the formula (I) in which R1, R2 and R3 independently of one another are C1-C6-alkyl, C1-C6-haloalkyl, C2-C6-alkenyl, C3-C10-cycloalkyl or benzyl or NR2R3 is a 5- to 10-membered heterocyclic radical, to a process for preparing compounds of the formula (I) wherein an appropriate 3-aminoacrylic ester is reacted with difluoroacetyl fluoride and to the use of compounds of the formula (I) in the process for preparing difluoromethyl-substituted pyrazol-4-ylcarboxylic acids and their esters.
Public/Granted literature
- US20130041147A1 Process for preparing 2-(aminomethylidene)-4,4-difluoro-3-oxobutyric esters Public/Granted day:2013-02-14
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