A system and an on-board-diagnosis method is provided for an exhaust aftertreatment system of an engine including a diesel particulate filter unit which encompasses a particulate filter in which soot can be oxidized by NO2 and constituents of the exhaust gas are deoxidized in a nitrogen-oxides reduction unit arranged downstream of the diesel particulate filter unit, wherein the exhaust gas flows from the diesel particulate filter unit to the nitrogen-oxides reduction unit. The on-board-diagnosis method includes estimating an NO2 content upstream of the nitrogen-oxides reduction unit, measuring at least one of an NOx or NO2 content upstream of the nitrogen-oxides reduction unit, performing a comparison between the estimated and the measured contents, and, based on the result of the comparison deciding on at least one conditioning step of the diesel particulate filter unit.