Invention Grant
US08598359B2 Biaryl substituted heterocycle inhibitors of LTA4H for treating inflammation
失效
用于治疗炎症的LTA4H的二芳基取代的杂环抑制剂
- Patent Title: Biaryl substituted heterocycle inhibitors of LTA4H for treating inflammation
- Patent Title (中): 用于治疗炎症的LTA4H的二芳基取代的杂环抑制剂
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Application No.: US12136874Application Date: 2008-06-11
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Publication No.: US08598359B2Publication Date: 2013-12-03
- Inventor: Vincent Sandanayaka , Jasbir Singh , Mark Gurney , Bjorn Mamat , Peng Yu , Louis Bedell , Lei Zhao , Rama K. Mishra
- Applicant: Vincent Sandanayaka , Jasbir Singh , Mark Gurney , Bjorn Mamat , Peng Yu , Louis Bedell , Lei Zhao , Rama K. Mishra
- Applicant Address: IS Reykjavik
- Assignee: Decode Genetics EHF
- Current Assignee: Decode Genetics EHF
- Current Assignee Address: IS Reykjavik
- Agency: Heslin Rothenberg Farley & Mesiti P.C.
- Main IPC: C07D211/20
- IPC: C07D211/20 ; A61K31/445
Abstract:
The present invention relates to a chemical genus of biaryl substituted heterocycle inhibitors of LTA4H (leukotriene A4 hydrolase) useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders. The compounds have general formula Ψ: An example is
Public/Granted literature
- US20090163462A1 BIARYL SUBSTITUTED HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION Public/Granted day:2009-06-25
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