发明授权
- 专利标题: Pyrrolidine inhibitors of IAP
- 专利标题(中): IAP吡咯烷抑制剂
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申请号: US12538794申请日: 2009-08-10
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公开(公告)号: US08609845B2公开(公告)日: 2013-12-17
- 发明人: Frederick Cohen , Vickie Hsiao-Wei Tsui , Cuong Ly , John A. Flygare
- 申请人: Frederick Cohen , Vickie Hsiao-Wei Tsui , Cuong Ly , John A. Flygare
- 申请人地址: US CA South San Francisco
- 专利权人: Genentech, Inc.
- 当前专利权人: Genentech, Inc.
- 当前专利权人地址: US CA South San Francisco
- 代理机构: Morrison & Foerster LLP
- 主分类号: C07D277/20
- IPC分类号: C07D277/20 ; C07D453/02 ; C07D471/14
摘要:
The invention provides novel inhibitors of IAP that are useful as therapeutic agents for treating malignancies where the compounds have the general formula I: wherein A, Q, X1, X2, Y, R1, R2, R3, R4, R4′, R5, R6 and R6′ are as described herein.
公开/授权文献
- US20090318409A1 PYRROLIDINE INHIBITORS OF IAP 公开/授权日:2009-12-24