- 专利标题： Molecules with effects on cellular development and function
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申请号： US11658980申请日： 2005-08-04
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公开(公告)号： US08617815B2公开(公告)日： 2013-12-31
- 发明人: Salman R. Khetani , Sangeeta N. Bhatia
- 申请人： Salman R. Khetani , Sangeeta N. Bhatia
- 申请人地址： US CA Oakland
- 专利权人： The Regents of the University of California
- 当前专利权人： The Regents of the University of California
- 当前专利权人地址： US CA Oakland
- 代理机构： Nelson Mullins Riley & Scarborough LLP
- 代理商 Debra J. Milasincic, Esq.
- 国际申请： PCT/US2005/027604 WO 20050804
- 国际公布： WO2006/015368 WO 20060209
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12N5/07
摘要：
This invention relates to methods to stabilize and/or improve the function of parenchymal cells. Also provided are systems of co-cultures of hepatocyte-stabilizing non-parenchymal cells used in bioreactor microenvironments to identify hepatic stabilizing factors by gene-expression profiling.