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公开(公告)号:US08617815B2
公开(公告)日:2013-12-31
申请号:US11658980
申请日:2005-08-04
CPC分类号: C12N5/067 , C12N2501/165 , C12N2501/42 , C12N2501/73 , C12N2501/998 , C12N2502/02 , C12N2506/00 , G01N33/5032 , G01N33/5067 , G01N33/5073
摘要: This invention relates to methods to stabilize and/or improve the function of parenchymal cells. Also provided are systems of co-cultures of hepatocyte-stabilizing non-parenchymal cells used in bioreactor microenvironments to identify hepatic stabilizing factors by gene-expression profiling.
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公开(公告)号:US20090202471A1
公开(公告)日:2009-08-13
申请号:US11658980
申请日:2005-08-04
CPC分类号: C12N5/067 , C12N2501/165 , C12N2501/42 , C12N2501/73 , C12N2501/998 , C12N2502/02 , C12N2506/00 , G01N33/5032 , G01N33/5067 , G01N33/5073
摘要: This invention relates to methods to stabilize and/or improve the function of parenchymal cells. Also provided are systems of co-cultures of hepatocyte-stabilizing non-parenchymal cells used in bioreactor microenvironments to identify hepatic stabilizing factors by gene-expression profiling.
摘要翻译: 本发明涉及稳定和/或改善实质细胞功能的方法。 还提供了用于生物反应器微环境中的肝细胞稳定的非实质细胞的共培养系统,以通过基因表达谱鉴定肝稳定因子。
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