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US08642596B2 Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arena viruses 失效
磺酰氨基脲，氨基脲和脲，其药物组合物和治疗出血热病毒的方法，包括与竞技场病毒相关的感染

Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arena viruses
摘要：
Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain novel semicarbazides, sulfonyl carbazides, ureas and related compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by hemorrhagic fever viruses is disclosed, i.e., including but not limited to Arenaviridae (Junin, Machupo, Guanavito, Sabia and Lassa), Filoviridae (ebola and Marburg viruses), Flaviviridae (yellow fever, omsk hemorrhagic fever and Kyasanur Forest disease viruses), and Bunyaviridae (Rift Valley fever).
摘要（中）：

公开了通过施用治疗有效量的某些新型氨基脲，磺酰基卡巴肼，脲和相关化合物来治疗病毒感染的化合物，方法和药物组合物。 还公开了制备化合物的方法和使用该化合物的方法及其药物组合物。 特别地，公开了治疗和预防由出血热病毒引起的病毒感染，即，包括但不限于：活细胞病毒科（Junin，Machupo，Guanavito，Sabia和Lassa），丝状病毒科（埃博拉病毒和马尔堡病毒），黄病毒科（Flaviviridae） 黄热病，o疮出血热和Kyasanur森林病毒）和布尼亚病毒科（裂谷热）。

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