发明授权
- 专利标题： Prevention of chlamydia infection using SIRNA
- 专利标题（中）： 使用SIRNA预防衣原体感染
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申请号： US11868788申请日： 2007-10-08
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公开(公告)号： US08648052B2公开(公告)日： 2014-02-11
- 发明人: Jonathan Braun , Lynn K. Gordon , Kaori Shimazaki , Madhuri Wadehra-Dhawan , Kathy A. Kelly
- 申请人： Jonathan Braun , Lynn K. Gordon , Kaori Shimazaki , Madhuri Wadehra-Dhawan , Kathy A. Kelly
- 申请人地址： US CA Oakland
- 专利权人： The Regents of the University of California
- 当前专利权人： The Regents of the University of California
- 当前专利权人地址： US CA Oakland
- 代理机构： Morgan, Lewis & Bockius LLP
- 代理商 Annette S. Parent
- 主分类号： C12N15/11
- IPC分类号： C12N15/11 ; A61K39/118
摘要：
The present invention provides methods and compositions useful in the treatment or prevention of Chlamydia infections. The methods and compositions inhibit the entry of Chlamydia into a host cell expressing EMP2 by interfering with the interaction between the Chlamydia and EMP2. The compositions include EMP2 nucleic acids and polypeptides as well as anti-EMP2 antibodies.
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