发明授权
- 专利标题： Nanofibrous scaffold comprising immobilized cells
- 专利标题（中）： 包含固定化细胞的纳米纤维支架
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申请号： US12954829申请日： 2010-11-26
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公开(公告)号： US08691543B2公开(公告)日： 2014-04-08
- 发明人: Glenn Gaudette , Matthew D. Phaneuf , Syed Ali , Brian Almeida , Helena Alfonzo , Katie Flynn
- 申请人： Glenn Gaudette , Matthew D. Phaneuf , Syed Ali , Brian Almeida , Helena Alfonzo , Katie Flynn
- 申请人地址： US MA Worcester
- 专利权人： Worcester Polytechnic Institute
- 当前专利权人： Worcester Polytechnic Institute
- 当前专利权人地址： US MA Worcester
- 代理机构： Burns & Levinson, LLP
- 代理商 Janine M. Susan; Jacob N. Erlich
- 主分类号： C12N11/08
- IPC分类号： C12N11/08 ; A61F2/00 ; C12N11/04 ; C12N5/07
摘要：
The invention is directed to a device and method to prevent migration of Human Mesenchymal Stem Cells (hMSCs) from a delivery site while allowing communication between the stem cells and native cardiomyocytes. The device is characterized by scaffold pore size, fiber diameter and biomaterial selection. The invention includes a two part polyurethane scaffold that prevents migration of stem cells, allows gap junction formation through pores and is packaged for minimally invasive delivery.
公开/授权文献
- US20110142804A1 NANOFIBER SCAFFOLD 公开/授权日：2011-06-16
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