Invention Grant
- Patent Title: Inhibitors of NF-κB activity
- Patent Title (中): NF-κB活性抑制剂
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Application No.: US12593550Application Date: 2008-03-28
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Publication No.: US08691764B2Publication Date: 2014-04-08
- Inventor: Zhiquan Zhang , Basil Rigas
- Applicant: Zhiquan Zhang , Basil Rigas
- Applicant Address: US NY Albany
- Assignee: The Research Foundation for the State University of New York
- Current Assignee: The Research Foundation for the State University of New York
- Current Assignee Address: US NY Albany
- Agency: Kenyon & Kenyon LLP
- International Application: PCT/US2008/058759 WO 20080328
- International Announcement: WO2008/121881 WO 20081009
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61P29/00 ; C12N15/00 ; C12N5/00 ; C12N5/02 ; A61P23/00 ; A61P35/00
Abstract:
The present invention provides a method for inhibiting NF-κB activity in a subject, the method comprising providing an agent capable of inducing expression of annexin 1, whereby said agent induces expression of annexin 1 and whereby said induced expression of annexin 1 inhibits NF-κB activity. Also provided are annexin 1 mimetics capable of binding to NF-κB and pharmaceutical compositions of such inducing and mimetic agents.
Public/Granted literature
- US20120004175A1 INHIBITORS OF NF-KB ACTIVITY Public/Granted day:2012-01-05
Information query
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