发明授权
- 专利标题： Auristatin derivatives and use thereof
- 专利标题（中）： Auristatin衍生物及其用途
-
申请号： US13702881申请日： 2011-06-06
-
公开(公告)号： US08722629B2公开(公告)日： 2014-05-13
- 发明人: Hans-Georg Lerchen , Beatrix Stelte-Ludwig , Sven Golfier , Joachim Schuhmacher , Ursula Krenz
- 申请人： Hans-Georg Lerchen , Beatrix Stelte-Ludwig , Sven Golfier , Joachim Schuhmacher , Ursula Krenz
- 申请人地址： US WA Bothell
- 专利权人： Seattle Genetics, Inc.
- 当前专利权人： Seattle Genetics, Inc.
- 当前专利权人地址： US WA Bothell
- 代理机构： Buchanan Ingersoll & Rooney PC
- 优先权： EP10165550 20100610; EP11158464 20110316
- 国际申请： PCT/EP2011/059300 WO 20110606
- 国际公布： WO2011/154359 WO 20111215
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K35/00 ; A61K38/08 ; A61K38/04 ; C07K5/00 ; C07K7/00 ; C07K16/00 ; C07K17/00
摘要：
The present application relates to novel derivatives of monomethylauristatin F, to processes for preparing these derivatives, to the use of these derivatives for treating and/or preventing diseases, and also to the use of these derivatives for preparing medicaments for treating and/or preventing diseases, more particularly hyperproliferative and/or angiogenic disorders such as, for example, cancerous disorders. Such treatments may be practised as a monotherapy or else in combination with other medicaments or further therapeutic measures.
公开/授权文献
- US20130157960A1 NOVEL AURISTATIN DERIVATIVES AND USE THEREOF 公开/授权日：2013-06-20
信息查询
IPC分类:
